Protective effects of various otoprotectant molecules on cisplatin-induced degeneration of hair cells and spiral ganglion neurons were measured.FIGS
Basic improvements usually appear by weeks one to two
However, combination studies are limited and no established guidelines exist for combining these peptides
What GHK-Cu adds to the formulation: Gene expression modulation across hundreds of genes including collagen genes (Type I, III), tissue inhibitors of metalloproteinases, anti-inflammatory mediators Collagen synthesis stimulation, specifically Type I and Type III collagen the structural proteins of skin, connective tissue, and many other tissues Anti-inflammatory signaling through investigated effects on TNF-, IL-6, and NF-B pathways Copper-peptide chemistry effects including cofactor activity for skin-relevant enzymes Skin-research and hair-research applications (the GHK-Cu literature in these areas is substantial) For the GHK-Cu deep-dive, see Copper Peptides Explained
If you need an isotonic solution one that matches the body's natural salt balance or you're working with a compound where preservative-free saline is specifically recommended, saline is the appropriate choice
