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AOD-9604 targets fat cells directly, promoting their breakdown, while MOTS-C improves overall metabolic function and insulin sensitivity

Use caution in patients with a history of anaphylaxis or angioedema to other GLP-1 receptor agonists because it is unknown whether such patients will be predisposed to serious reactions with semaglutide

Administering near target fat areas Some protocols suggest administering AOD-9604 near areas of stubborn fat with the theory that local administration may enhance local effect

Consistency over perfection: Perfect diet and training for 4 weeks beats mediocre adherence for 12 weeks