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By protecting mitochondria from oxidative damage, SS-31 may reduce one of the upstream triggers of autoimmune-associated inflammation

Moreover, their limited tolerability, adverse effects, and variable patient responses emphasize the urgent need for safer, more effective, and disease-modifying therapeutic strategies (Zhang et al., 2024)

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RAW264.7 cells were infected with HSV-2 and ROS formation at different time points was monitored by live microscopy using the oxidant-sensitive fluorescent probe CM-DCFDA