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CPT1A can modulate the succinylation of enolase 1 to enhance the growth of breast cancer (Kurmi et al., 2018) and the succinylation of S100A10 to facilitate the spread of gastric cancer (Wang et al., 2019)

A randomized, double-blind, placebo-controlled trial in 28 older women (ages, 65-70 years) found no effect of L-carnitine supplementation (1.5 g/day for 24 weeks) on serum pro-inflammatory cytokine concentrations, body mass and composition (lean [fat-free] mass and skeletal muscle mass), or measures of skeletal muscle strength (123)

Blanco for providing mouse cell lines

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57 Genetic ablation of NLRP3 significantly reduces the release of cleaved IL-1 and IL-18, thereby alleviating APAP-induced liver injury