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We note that PRX classification based on active site profiles has been adopted in recent literature, such as 46 and 47 , although there still are exceptions, such as 48,49,50,51

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Apigenin was shown to significantly decrease erythrocyte cell size, increase cytosolic Ca 2+ concentrations and PS exposure (Zbidah et al., 2012), and to display antimalarial activity in mice (against P

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