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UV can promote the translocation of Bax to the mitochondria [59], increasing the expression of p53 and Bax, and decreasing the expression of Bcl-2 [60]

The biological significance of substrate inhibition: a mechanism with diverse functions

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Evaluation of the safety, efficacy, and mechanism of action of obexelimab for the treatment of patients with IgG4-related disease: an open-label, single-arm, single centre, phase 2 pilot trial

This improved tolerance makes it suitable for longer-term use