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doi: 10.1111/epi.12570 29

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The Canadian research community has increasingly explored these combinations, particularly as weight loss medications become more accessible

The compound appears to work by increasing intracellular NAD+ levels (through preventing nicotinamide consumption by NNMT), which activates sirtuins and enhances mitochondrial function and fatty acid oxidation, while also promoting a phenomenon called "browning" of white adipose tissue - the transformation of energy-storing white fat cells into metabolically active beige/brown adipocytes that burn fatty acids for thermogenesis rather than storing them

By deeply interrogating these resources, AI can rapidly identify bioactive compounds linked to depression and elucidate their underlying mechanisms of action