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These inhibitors act through two mechanisms: i) interaction with the copper-dependent cofactor ( e.g ., thiram, disulfiram, MCP)

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Redox phospholipidomics discovers pro-ferroptotic death signals in A375 melanoma cells in vitro and in vivo

Nat Rev Immunol 24:858877 Beil WJ, Meinardus-Hager G, Neugebauer DC, Sorg C (1992) Differences in the onset of the inflammatory response to cutaneous leishmaniasis in resistant and susceptible mice

2) During the aging and damage process of hair follicles, ferritin releases ferrous ions, promoting the formation of free radicals and causing more oxidative reactions