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Its anti-inflammatory effects on NFkB a key mediator of age-related inflammatory disease and its DNA repair activity suggest potential relevance in broader regenerative medicine, though most of these applications remain under investigation

In Hashimotos thyroiditis (HT), major sources of oxidative stress include misfolded proteins, dysbiosis and molecular mimicry, self-tolerance defects linked to AIRE gene dysfunction, and irregularities in thyroid protein folding (da Silva et al

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In lyophilized form, FOXO4-DRI is stable for 36 months

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