Steroids should be used with caution in nonspecific ulcerative colitis, if there is a probability of impending perforation, abscess or other pyogenic infection, also in diverticulitis, fresh intestinal anastomoses, active or latent peptic ulcer, renal insufficiency, hypertension, osteoporosis, and myasthenia gravis
The FDA has not approved MOTS-c for human use, and in 2023, the agency clarified that it cannot legally be used in compounded medications
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Early research is mostly preclinical, so it should not be treated as a proven anti-aging or fat-loss treatment
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