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Position in ingredient list: EU and FDA cosmetic labeling requires ingredients listed in descending order of concentration down to 1 percent, after which order is arbitrary
Want to see what GHK-Cu actually does to skin
Patient selection considerations include: Topical delivery : Suitable for maintenance, prevention, and mild aging concerns Injectable delivery : Appropriate for significant skin damage, deep wrinkles, and hair loss Combination protocols : Optimal for comprehensive regenerative programs Troche Delivery for Sustained Systemic Effects Troches (dissolvable lozenges placed between the cheek and gum) represent another delivery option for GHK-Cu
FIGURE 4 This is complicated because as a polar, charged tripeptide, transport of GSH is significantly inhibited by the blood-brain barrier (BBB), thus limiting effective delivery to brain-resident immune cells such as microglia which are central drivers of neuroinflammatory pathology (Valdovinos-Flores and Gonsebatt, 2012