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doi: 10.1046/j.1365-3083.2002.01063.x 142 GehDGordonC

Iron derived from autophagy-mediated ferritin degradation induces cardiomyocyte death and heart failure in mice

Arcan P, Bozkurt O, Cavusoglu D, Gencpnar P, Haspolat S, Duman O, Olgac Dundar N

It was developed by Daiichi Sankyo and co-developed with AstraZeneca, and has received FDA approval in 2025 for the treatment of advanced breast cancer and lung cancer in specific patient groups

81,82 Antiulcer and gastroprotective agents Herbs with gastroprotective and antiulcer properties offer significant advantages over synthetic agents, particularly for long-term use in GERD, gastritis, and peptic ulcer disease