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Broader solid tumor studies corroborate that pharmacological inhibition of CAF-mediated Gln synthesis disrupts tumor metabolic fitness, suggesting combinatorial targeting of tumoral and stromal glutamine metabolism, particularly through dual GLS1/ECM pathway inhibition, may offer promising therapeutic avenues for advanced prostate cancer (196)

Elevated TSLP expression has been detected in the airway epithelium and bronchoalveolar lavage (BAL) fluid of individuals with asthma, where it correlates with disease severity and progressive loss of lung function [34]

When hepatocytes are damaged, the bilirubin metabolism pathway is impaired, leading to varying degrees of increase in blood bilirubin, especially direct bilirubin [63]

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Plans call for a diver to seal up a crack this fall, using a special polymer coating