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Hematol Oncol Stem Cell Ther 2016

SYN1436 is a selective human neonatal Fc receptor ( hFcRn ) antagonist with an IC 50 of 2.4 nM

Philos Trans R Soc Lond B Biol Sci 2005

The two major pathways for the degradation of proteins involve the selective elimination through the ubiquitin-proteasome system (UPS) and removal through chaperone-mediated autophagy (CMA) (128)