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They are not for human or veterinary use , not intended for diagnosis, treatment, cure, or prevention of any disease, and must be handled exclusively by qualified research professionals in controlled laboratory environments

[163, 165] have reported that off-target toxicity in peripheral organs remained minimal, although they emphasised that excessively high doses or positively charged CQDs may still provoke ROS formation, mitochondrial dysfunction, or the activation of inflammatory pathways [163, 165]