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Recently, the obvious senescence phenotypes in keloid lesions and fibroblasts were found and senolytic dasatinib was demonstrated to have antifibrotic effects in keloids 14,15

Proc Natl Acad Sci U S A (1998) 95(1):1149.10.1073/pnas.95.1.114 128 ZhangJGFarleyANicholsonSEWillsonTAZugaroLMSimpsonRJet alThe conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation