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European Journal of Clinical Pharmacology 77(11):16491663 Zhu C et al (2017) Exogenous melatonin in the treatment of pain: a systematic review and meta-analysis

As far as NAD+ precursors potential to slow aging goes, a year-long study with adults aged 54 to 84 showed that NMN supplementation was associated with significantly reduced acceleration of epigenetic agea measure of how fast cells are aging based on chemical modifications to DNA

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