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Knocking down ACTL6A also decreased the GCLC protein expression level in GC cells (Supplementary Fig 5c)

Insecticides, pesticides, and environmental toxins (heavy metals, bisphenol A, and dioxins) lead to a reduction in male fertility, causing an alteration in sperm DNA both directly and indirectly, through the production of ROS, with a consequent reduction in the number of ejaculated spermatozoa and the presence of morphologically abnormal spermatozoa in seminal fluid [8,9,10,11,12]

10.1016/j.bpobgyn.2010.10.011 102 PsychoyosA

Cell death in the liver may be exacerbated by a deficiency in glutathione, which can also lead to fatty liver disease

Studies in apolipoprotein E-deficient mice, an animal model of atherosclerosis, found that coenzyme Q 10 supplementation with supra-pharmacological amounts of coenzyme Q 10 inhibited lipoprotein oxidation in the blood vessel wall and the formation of atherosclerotic lesions (23)