Proposed pathways include modulation of multiple neurotransmitter systems (influencing serotonin, dopamine, norepinephrine, GABA, glutamate levels), possible involvement of NMDA receptors, alpha-1 adrenergic signaling (e.g., potentiating pineal acetyltransferase activity), inhibition of somatostatin release via dopaminergic routes, reduced ACTH/cortisol for stress buffering, and stimulated growth hormone or somatoliberin secretion
We thank the Cleveland Clinic Cardiology Fellowship Program for providing support from the Ralph C
doi: 10.1016/j.jmhi.2013.02.003 44 OdoSTanabeKYamauchiM
Its mechanism of action involves binding to the HGF receptor, also known as c-Met
Additionally, more than one receptor type and different G-protein coupling of neuropeptide receptors in different tissues lead to variable effects of the same neuropeptides in different tissues/cell types [24,25,26,27,28,29,30,31,32,33,34,35,36]