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Meets USP standards

The absence of verified pharmacokinetics and product verification prevents evidence-based recommendations regarding discontinuation timing, perioperative safety, and postoperative resumption, leaving surgeons unable to quantify risk in elective operative settings

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Therefore, developing animal models and in vitro three-dimensional culture systems that more closely mimic human pathophysiological processes is vital

[11] [4] Measurable improvements in serum B12 usually occur within four to eight weeks, though normalisation may take three to six months depending on baseline severity