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Figure 7b illustrates the cardiac tissue of the positive hypercholesterolemic group (G2), which exhibits myocyte atrophy, increased fat accumulation, inflammation, fibrosis, and focal fibrotic myocitis

This low-grade, long-term inflammation spreads throughout the body, irritating joint linings, breaking down cartilage matrix integrity, and hyper-sensitizing local nerve pathways

In experimental models of SCI, this protein has been found to be significantly elevated for up to 11 months in sensory axons, neurons, astrocytes, and ependymal cells, despite consequent loss of nerve tissue at the site of injury

This indicates that changes in the synthetic pathway under salt stress further increase the energy consumption of proline metabolism in R

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