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The main risks stem from its unapproved status and potential for improper compounding

However, large-scale human trials remain limited and results vary

Consequently, the accurate attribution of the obtained peptide effects, particularly for skin defect healing (where unlike uncertain healing attribution of other peptides which are given with carriers (4-9), BPC 157 is given alone and thereby acts directly), the therapeutic success of BPC 157 over the external fistulas model (10-12) and now in duodenocutaneous fistulas further emphasized the real healing congruence of the skin healing and other gastrointestinal tissues healing

Overall, studies consistently converge on the idea that oxidative stress is a key driver of canine cognitive dysfunction, mirroring mechanisms described in human neurodegenerative disease

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