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Peruvian Medical Oncology Society Conference

The consideration of cysteine during these simulations were important, as cytosolic cysteine is the rate limiting amino acid precursor for synthesis of GSH, via the -glutamylcysteine synthetase (GCS) enzyme, and this is a function of its reduced concentration compared to the other precursors, glycine and glutamate

Authors concluded that combining NRT with behaviour change counselling resulted in a significantly higher quit rates and lower cotinine levels, but significant impact on patient-related or microbiological outcomes were not detected (Sharma et al., 2018)

doi: 10.1172/JCI0213462 191 ViglioSBakEGSchoutenIGMIadarolaPStolkJ