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The impacts of adolescent alcohol and marijuana use onset on cognition, brain structure, and function

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deficiencies of vitamin B12, folate or niacin, and infective causes including cryptococcal meningitis, HIV, Lyme disease, progressive multifocal leukoencephalopathy, subacute sclerosing panencephalitis, syphilis and Whipple's disease

Systematic reviews and meta-analyses suggest that frequent or prolonged prenatal exposure may be associated with (1925): Higher rates of hyperactivity and attention-related disorders Increased likelihood of ADHD medication use Elevated risk of autism -related neurobehavioral patterns Increased childhood asthma risk, particularly with late-pregnancy exposure A large systematic review of 46 studies found that neurodevelopmental risks appeared dose-dependent and were more pronounced in higher-quality studies (26)

doi: 10.1172/JCI16801