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One widely held theory is that patients with a genetic predisposition and abnormal bacteria colonization, or dysbiosis, experience a gradual development of lymphocytes which are known as B cell clones which are susceptible to autoreactivity

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doi: 10.1016/0197-4580(90)90110-l

This type of infection is also an example of where a functional practitioner may choose to use a combination of both conventional and natural treatment methods to address a particular root cause