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PMID: 29155147): 5-Amino-1MQ showed NNMT selectivity with IC50 of 1.2 microM Reduced body weight and white adipose mass in diet-induced obese mice over 11 days No effect on food intake, suggesting metabolic rather than appetitive mechanism Nicotinamide N-methyltransferase inhibition mimics and boosts exercise-mediated improvements in muscle function in aged mice , published in Scientific Reports (Dimet-Wiley AL et al., 2024

Rather than being outcomes themselves, the peptides may be used to probe: How cells move and organize (often discussed with TB4-related actin dynamics)

Some researchers follow 2-months-on, 1-month-off cycling patterns to prevent potential receptor downregulation

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A 2.5mg dose at this concentration requires 75 units instead of 50