NAC is also important for phase 2 liver detoxification, which is a crucial step in neutralizing potential toxins created during phase 1 detoxification
In homeostasis conditions, GSH is the most efficient physiological reducing agent with the highest bioavailability (~ 10 mM) in the intracellular environment where it is synthesized, except in epithelial cells [23]
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Adaptation of the Master Antioxidant Response Connects Metabolism, Lifespan and Feather Development Pathways in Birds
4.2 Hyperthyroid-induced hepatic disease Hyperthyroid-induced hepatic disease involves liver injury caused by excessive thyroid hormones, resulting in hepatocellular degeneration, necrosis, and hepatomegaly (106), and often presents with jaundice, elevated transaminases, or cirrhosis (107)