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7 A Clinical Perspective Despite limited case reports and studies and our general caveats with regard to research confounds with antioxidants, NAC appears to be promising in a number of psychiatric syndromesparticularly those associated with oxidative stress (e.g., schizophrenia and bipolar disorder) and impulsive/compulsive symptoms (e.g., trichotillomania, pathological nail biting, gambling, and substance misuse)

Moreover, Quercetin was also found to reduce organophosphorus pesticide mixture-induced nephrotoxicity by regulating fatty acid, energy and sex hormone metabolism, protecting antioxidant defense systems and reducing DNA damage (Qi et al., 2017)

Further analyses, controlling for these variables, demonstrated that 8-iso-PGF2 serum levels were significantly elevated in the depression cohort compared to the control group