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(PubMed) Contempre B, Duale NL, Dumont JE, Ngo B, Diplock AT, Vanderpas J

Pretreatment with candesartan (1 mg/kg/d, for 3 d before the LPS treatment) lessens LPS-induced ACTH and corticosterone release and reduces gene expression of cyclooxygenase-2 (COX-2), IL-6, and TNF- (105)

This creates constant energy demand, leading to a massive influx of oxygen and the production of reactive oxygen species (ROS) that can damage the very cellular machinery that powers the cell

This is how glutathione reacts with oxidants and toxic metals

If you suspect that you could possibly have a glutathione hypersensitivity, discuss the matter with a medical professional to confirm