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The RAGE axis: a fundamental mechanism signaling danger to the vulnerable vasculature

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Furthermore, enteral nutrition (EN) is recommended as the primary nutritional support for patients with inadequate oral intake, as it may alleviate acute radiation-induced diarrhoea and modulate the gut microecology 207

Native IGF-1 binds with high affinity to insulin-like growth factor binding proteins (IGFBPs), which sequester the peptide in circulation and substantially reduce its free bioavailable fraction

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