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In pediatric patients with trimethylaminuria (FMO3 deficiency), the use of metronidazole, amoxicillin, and neomycin can partially inhibit the conversion of choline to TMA, with neomycin being the most effective, followed by amoxicillin, and metronidazole being the weakest effective among them

10d,e) and still showed extremely prolonged prothrombin times (a parameter of vitamin K-dependent coagulation factors) in contrast to Fsp1 +/ mice (Fig