Proteolytic action of NSPs is controlled endogenously by the serpin (serine proteinase inhibitor) superfamily of proteins (e.g., alpha1-antitrypsin (AAT), alpha1antichymotrypsin, monocyte NE inhibitor) and the chelonianin family of canonical inhibitors (elafin, secretory leukocyte protease inhibitor) (82, 83)
PUFA-PE production depends on coordinated action between acyl coenzyme A synthetase long-chain family member 4 (ACSL4) and lysophospholipid acyltransferase 3 (LPCAT3), which collectively activate and incorporate PUFAs (e.g., docosahexaenoic acid, arachidonic acid) into membrane lipids (43)
Western blotting HCT116 cells were seeded in a six-well plate and treated with GSTO1 inhibitors for 24 h
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