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As cirrhosis gets worse, the liver begins to fail

FIGURE 4 Overexpression of RcGPX4 Enhanced Cold Tolerance at Seed Germination but Reduced Freezing Tolerance at Seedlings Our previous study showed that the protein abundance of RcGPX4 was increased in cold-stressed imbibed seeds (Wang et al., 2019)

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The kidneys normally regulate potassium balance, but when renal function is compromised, excess potassium can accumulate, leading to cardiac arrhythmias