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This is likely an important, if not necessary, fundamental change in how we feed ourselves, but it is recognized that this could increase the prevalence of vitamin B12 deficiency because the vitamin is not found in plant-based foods (106, 107)

[1] Unlike the folic acid derivative leucovorin, folic acid is not clinically useful in offsetting the action of folate reductase inhibitors because it requires the enzyme dihydrofolate reductase for activation

Cel Biol 21, 122132

Because lipotropics directly aid fat breakdown and are closely related to B vitamins, when used together they are thought to intensify each others effects

So Im not going to assume I know everything just because I have top notch expertise in the field