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It has also been shown to reduce cardiovascular events in patients with end-stage renal disease

However, a limited number of patients respond effectively, primarily due to drug resistance and the absence of reliable biomarkers for patient stratification

siCTR transfected cells ( A ) and siCTR transfected cells treated with RSL3 ( B , D ) were used as comparator in the statistical analysis

This dilemma underscores the importance of achieving redox balance rather than solely focusing on reducing oxidative markers [83]