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In some embodiments, the formulations described herein have a practical osmolarity of about 100 mOsm/L to about 1000 mOsm/L, about 200 mOsm/L to about 800 mOsm/L, about 250 mOsm/L to about 500 mOsm/L, about 250 mOsm/L to about 350 mOsm/L, about 250 mOsm/L to about 320 mOsm/L, or about 280 mOsm/L to about 320 mOsm/L

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Intraperitoneal injections of trimetazidine (25 mg/kg/day for 5 days) in rats before seizure induction prevented apoptosis of hippocampal neurons [138]

It is worth mentioning that iodoacetic acid (IAA), the most genotoxic iodinated disinfection byproduct known in drinking water, has recently been shown in in vitro and in vivo studies to act as a potential thyroid disruptor at various levels

(2019, February 13)