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Besides, it stimulated expression of early growth response 1 (egr-1) gene responsible for cytokine and growth factor generation and early extracellular matrix (collagen) formation (but also its repressor nerve growth factor 1-A binding protein-2 (nab2)) (44)

Eat foods rich in B12 - Including animal products like beef, eggs, and dairy products can help restore levels through a healthy diet

Collagen also exhibits an affinity for water, and it appears to hydrate the skin cells and Extracellular Matrix when it penetrates the skin barrier

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