Benefits of B1 : Thiamin Vitamin B1 helps prevent complications in the: nervous system brain muscles heart stomach intestines It is also involved in the flow of electrolytes into and out of muscle and nerve cells
Researched effects In a diet-induced-obese mouse study (Neelakantan et al., Biochemical Pharmacology, 2018), subcutaneous 5-Amino-1MQ (20 mg/kg, three times daily, roughly 11 days) produced about 5.1% body-weight loss versus continued weight gain in untreated controls, roughly 35% less epididymal white fat mass, smaller adipocytes, lower plasma cholesterol, and improved glucose tolerance, with no reported change in food intake and no observed adverse effects in the mice
While this explanation touches on some interesting concepts, there are several points that need clarification and might be oversimplified or speculative: Lets start with neuronal compensation
Who Should Avoid MOTS-c Pregnant or breastfeeding individuals People with an active cancer diagnosis, since MOTS-c may affect prostate and breast cancer pathways Those taking AMPK-activating medications like metformin, thiazolidinediones, or aspirin Anyone on insulin or with uncontrolled diabetes without medical supervision Minors and adolescents Athletes in tested sports, since MOTS-c is on the WADA Prohibited List under Section S4 Anyone without access to lab-verified research peptides MOTS-c vs Other Metabolic Peptides (High-Level Comparison) MOTS-c vs Semaglutide MOTS-c works through the mitochondrial pathway with gradual, muscle-preserving results
Even worse, with lower levels of stomach acid comes the perfect breeding ground for gut bacteria that consume your bodys limited supply of vitamin B12
