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Still, it is safe to conclude that a vicious circle between liver fibrosis, cirrhosis, portal hypertension, and pathologic angiogenesis did not occur, or, once it had already advanced, there was a rapid reversal [118] (Figure 2, Table 2)

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But some studies suggest that creatine also can make cancer more likely to spread

Likewise, due to the large presence in human fetuses and adult tissues (in situ hybridization and immunostaining) [14], the concept holds a regulatory physiologic role in bodily functions [14], also based on similar beneficial effects in other species (i.e., birds [73] and insects [74,75,76])

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