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In addition to catalyzing GST reactions and S -(phenacyl)glutathione reduction, the enzyme also catalyzes thioltransferase reactions and reduction of dehydroascorbate and monomethylarsonate (V) (Board and Anders, 2007)

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Pregnancy and lactation safety has not been systematically studied, and as with most cosmetic and research compounds lacking definitive pregnancy safety data, conservative practice typically suggests avoiding use during pregnancy unless clearly needed, though the natural occurrence of GHK-Cu in the body and minimal systemic absorption from topical use suggest risk is likely to be low

Discussion 1) The research team of Lau et al evaluated the efficacy and safety of the amylin analogue Cagrilintide for weight management