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Vacuoles are constantly undergoing fission and fusion events when cells are early in their chronological lifespan, which implies the membrane microdomains that only form after reaching stationary phase when vesicular trafficking has decreased would likely have less impact on the vacuolar fission/fusion process

In parallel, matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDIMSI) allows label-free, nearsingle-cell-resolution mapping of thousands of metabolites directly in intact tissue sections while preserving spatial architecture (97, 98)

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This is because people with a greater body weight have more blood and water in their bodies, which assists in the dilution of alcohol