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doi: 10.1002/jssc.200700261 82 FernandesAJDFerreiraMRARandauKPde SouzaTPSoaresLAL

Cancers , 15(3), 910

Key Takeaways on What Is BPC-157 BPC-157 is a synthetic 15-amino-acid peptide derived from a protein found in human gastric juice

Oxidants/Antioxidants in the Liver and Lung of Individuals with Inherited Alpha-1 Antitrypsin Deficiency Severe inherited alpha-1 antitrypsin deficiency (AATD) is a monogenic, autosomal, co-dominant, inherited disease associated with a risk for developing liver disease at any age and/or early onset emphysema

The critical role of Gpx4 is underscored by the fact that whereas Gpx1-knockout mice are fully viable, Gpx4-knockout animals demonstrate embryonic lethality, and Gpx4 +/ cell lines are markedly sensitive to inducers of oxidative stress, including -irradiation, tert -butyl-hydroperoxide, and hydrogen peroxide, as compared with cell lines derived from wild-type control littermates (147)