Role of HDACs in epilepsy Although the pathogenesis of epilepsy has not been fully established, excitotoxicity, oxidative stress and neuroinflammation are regarded as the triads of epileptogenesis, a process during which triggers of brain insults such as status epilepticus by chemoconvulsants, infection or cerebrovascular disease include and the brain undergoes a cascade of morphological and functional changes prior to the onset of spontaneous recurrent seizures in chronic epilepsy [98], and epilepsy-associated neurodegeneration
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Mao Y, Ma S, Liu C, Liu X, Su M, Li D, et al
Am J Med Genet C Semin Med Genet 142 C:7785
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