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Natural IGF-1 gets grabbed almost immediately by binding proteins that shuttle it around and limit its activity

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Future trials should also measure important outcomes such as the clinical signs and symptoms of vitamin B 12 deficiency, health related-quality of life, socioeconomic effects, and report adverse events adequately, preferably in a primary care setting. Clinical practice guidelines British Columbia Medical Services Commission (MSC)

By d 56, neither group was significantly improved compared with baseline (ARA 290 = 1.8 2.3 and placebo = 3.1 2.2)