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However, untreated varicose veins are associated with increased risk of deep vein thrombosis potentially deadly blood clots in the legs (Shaydakov 2016)

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What makes AOD-9604 unique is its selective action on fat metabolism without producing the other effects associated with full-length human growth hormone, such as increased blood glucose levels, insulin resistance, or excessive IGF-1 production

10.1186/s12951-020-00668-5 128 WangX.YaoM.MaL.YuP.LuT.ZhangL.et al (2021)

Continuous outcomes were analyzed using ANCOVA, with randomized treatment as a factor and baseline body weight as a covariate, while categorical data were analyzed with binary logistic regression