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FAE mediate their anti-psoriatic effects via activation of several cellular pathways that induce T-cell apoptosis or prevent release of proinflammatory cytokines (Figure 1)

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In comparison, colon crypts from the D3-Veh group were unable to self-expand, displayed less budding, and greater cell death and degradation, whereas crypts from IPA-treated colitic mice had superior budding and organoids forming ability (Fig