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for the incretin comparison, see Semaglutide vs Tirzepatide

Research community protocols typically restrict dosing to the morning

Factors such as initial B12 levels, underlying medical conditions, certain medications, advanced age, and injection frequency can affect the absorption and utilization of B12, possibly shortening the duration of action

Therefore, for anyone considering such a combination, the following apply: Extreme Caution and Medical Supervision: This is not a self-experimentation endeavor