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According to Venuka Wick, MD, an assistant clinical professor in the department of family medicine at University of Washington Medicine in Seattle, its best to only take supplements under the guidance of a healthcare provider, as too much of certain vitamins can be harmful

Appetite effects are not strongly characterized in either direction

For instance, some of these authors run clinics that offer BPC-157 as a treatment, creating a clear conflict of interest

Combining two compounds with unknown human pharmacokinetics, based on proposed mechanisms from separate animal studies, compounds the uncertainty rather than resolving it