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Other anti-FAP bispecific antibodies featured with FAP-targeting and immunomodulatory effects have also been developed [281]

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Recent studies have also shown that SARS-CoV-2 induces ferroptosis through distinct viral proteins: the membrane protein promotes membrane associated RING-CH-Type Finger 1(MARCHF1)/GPX4-mediated ferroptosis by enhancing lipid accumulation, while the accessory protein Orf7b triggers both apoptosis and ferroptosis (Sun et al., 2025)

doi: 10.1371/journal.pone.0172486