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To assess the clinical relevance of serine metabolism in lung cancer, we analyzed TCGA data and observed significant upregulation of key serine synthesis enzymes (PHGDH, PSAT1, PSPH, SLC1A4) and transporters (SLC2A1, SLC1A4, SLC1A5) in tumors compared to normal tissues (Fig

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Depletion of glutathione by buthionine sulfoxine is cytotoxic for human neuroblastoma cell lines via apoptosis